Details
Offer Chemical Raw Material 4-HYDROXY-3-NITROPHENYLACETIC ACID 10463-20-4 In Stock
- Molecular Formula: C8H7NO5
- Molecular Weight: 197.147
- Appearance/Colour: yellow crystalline powder
- Vapor Pressure: 5.38E-07mmHg at 25°C
- Melting Point: 146-148 °C(lit.)
- Refractive Index: 1.5700 (estimate)
- Boiling Point: 396.4 °C at 760 mmHg
- PKA: 4.25±0.10(Predicted)
- Flash Point: 179 °C
- PSA： 103.35000
- Density: 1.55 g/cm3
- LogP: 1.45070
4-HYDROXY-3-NITROPHENYLACETIC ACID(Cas 10463-20-4) Usage
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Synthesis Reference(s) |
Journal of Medicinal Chemistry, 30, p. 1166, 1987 DOI: 10.1021/jm00390a009 |
|
General Description |
4-Hydroxy-3-nitrophenylacetic acid enhances the ice-nucleation activity of Xanthomonas campestris. |
InChI:InChI=1/C8H7NO5/c10-7-2-1-5(4-8(11)12)3-6(7)9(13)14/h1-3,10H,4H2,(H,11,12)/p-2
10463-20-4 Relevant articles
Highly efficient and stable catalyst for peroxynitrite decomposition
Geletii,Bailey,Cowan,Weinstock,Hill
, p. 792 - 794 (2001)
The new cobalt substituted-polyoxometala...
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Shibata,Noda,Ogura,Sogabe,Sawa
, p. 1751 - 1753 (2000)
During a photo-induced catalytic reactio...
RAPID DECOMPOSITION OF PEROXYNITRITE BY MANGANESE PORPHYRIN-ANTIOXIDANT REDOX COUPLES
Lee, Jinbo,Hunt, Julianne A.,Groves, John T.
, p. 2913 - 2918 (1997)
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Catalase Catalyzes of Peroxynitrite-mediated Phenolic Nitration
Kono, Yasuhisa,Yamasaki, Tomoaki,Ueda, Akane,Shibata, Hitoshi
, p. 448 - 452 (1998)
Catalase catalyzed the peroxynitrite-med...
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10463-20-4 Process route
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156-38-7
4-hydroxyphenylacetate
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102-32-9
3,4-dihydroxyphenylacetate
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10463-20-4
4-hydroxy-3-nitrophenylacetic acid
| Conditions | Yield |
|---|---|
|
With
sodium peroxynitrite;
In
phosphate buffer;
at 20 - 25 ℃;
pH=7.0;
Further Variations:;
Solvents;
Kinetics;
|
-
-
156-38-7
4-hydroxyphenylacetate
-
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10463-20-4
4-hydroxy-3-nitrophenylacetic acid
| Conditions | Yield |
|---|---|
|
With
nitric acid; acetic acid;
5 deg C, 1 h -> room temperature, 1 h;
|
73.5%
|
|
With
nitric acid;
In
acetic acid;
|
70%
|
|
With
nitric acid;
In
acetic acid;
at 15 ℃;
for 0.333333h;
|
69%
|
|
With
nitric acid; acetic acid;
at 5 ℃;
for 0.916667h;
|
67.2%
|
|
With
nitric acid;
In
(2S)-N-methyl-1-phenylpropan-2-amine hydrate; acetic acid;
|
65%
|
|
With
nitric acid; acetic acid;
at 0 - 20 ℃;
for 2h;
|
64%
|
|
With
nitric acid;
In
water;
at 20 ℃;
|
63.9%
|
|
With
nitric acid; acetic acid;
at 10 - 15 ℃;
for 2.5h;
|
62%
|
|
With
nitric acid; acetic acid;
In
water;
at 10 - 15 ℃;
for 2.5h;
|
62%
|
|
With
sodium hydroxide; phosphate buffer; Peroxynitrite anion;
K7[CoAlW11O39]*15H2O;
In
water;
at 25 ℃;
pH=7.4;
|
40%
|
|
With
nitric acid; acetic acid;
at 0 ℃;
for 1h;
|
39%
|
|
With
Mn(III)TMPyP; Nitrate; ascorbic acid;
Product distribution;
other reagents;
|
|
|
With
potassium phosphate; 2,2-Dichloropropionic acid; peroxynitrite; bovine liver catalase;
Product distribution;
various reaction conditions;
|
|
|
With
nitric acid;
at 0 ℃;
|
|
|
With
titanium(IV) oxide; sodium nitrite;
In
phosphate buffer; tert-butyl alcohol;
for 1h;
pH=7.4;
UV-irradiation;
|
|
|
With
nitric acid;
In
water; acetic acid;
|
|
|
With
nitric acid;
In
water; acetic acid;
|
|
|
With
nitric acid;
In
water; acetic acid;
|
|
|
With
nitric acid;
In
acetic acid;
at 20 ℃;
for 2h;
Cooling;
|
|
|
With
nitric acid; acetic acid;
at 20 ℃;
|
|
|
With
nitric acid;
In
water; acetic acid;
|
|
|
With
nitric acid; acetic acid;
at 15 ℃;
for 1h;
|
20 g
|
|
With
nitric acid; acetic acid;
at 20 ℃;
for 2h;
|
5 g
|
10463-20-4 Upstream products
-
156-38-7
4-hydroxyphenylacetate
10463-20-4 Downstream products
-
10463-21-5
3-nitro-4-hydroxyphenylacetyl chloride
-
185104-75-0
N-[2-(3,4-Bis-benzyloxy-phenyl)-ethyl]-2-(4-hydroxy-3-nitro-phenyl)-acetamide
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1027948-18-0
2-(4-Hydroxy-3-nitro-phenyl)-N-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-N-methyl-acetamide
-
51234-85-6
dl-2-(p-chlorophenyl)-5-benzoxazolylacetic acid
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